What is this test?
Haptoglobin is a protein from the liver that binds free hemoglobin after breakdown of red blood cells. It also changes during inflammation.
Why might it be ordered?
- To assess whether anemia may be related to accelerated destruction of red blood cells.
- As part of an evaluation of liver function or inflammatory response.
What sample is needed?
A healthcare professional collects a venous blood sample. Depending on the method, the laboratory uses serum or plasma.
How should you prepare?
Tell the laboratory about all medicines, hormone treatments, vitamins and supplements you take. Do not stop or change treatment unless your clinician tells you to. Follow any instructions about fasting and the time of collection.
How should you understand the result?
A low value may support the presence of hemolysis, but also occurs with reduced formation in the liver. Inflammation can increase the value and mask hemolysis. Your result is interpreted using the reference interval on the laboratory report and in the context of your symptoms, medical history and other test findings.
Sources and editorial status
This patient-facing text is an editorial draft. It should be approved by a laboratory physician before official publication.